running rx 6600 on a pci-e gen 2 slot

pcie x 16 slot
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PCIe x1 and 16 lane PCIe x16 It is a serial bus point-to-point protocol General processors use the smallest PCI x1 slots Graphic cards use the longest

pcie4 slot A x8 card will work in an x1 slot, but will be limited to x1 speeds A x8 card will also work fine in a x4 slot It will be limited to x4 speeds

pcie 4 slot if the slot is open like that, you should be good to go if it's not open, you could a) use another riser to adapt the x8 to x16, or b)